Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn
Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes inflammation throughout the gut, leading to symptoms including abdominal pain, diarrhea, and weight loss. The disease is difficult to treat and often requires hospitalization.
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Integrative analysis of > 300,000 single-cell profiles from five
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Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy - ScienceDirect
Single-cell RNA sequencing reveals dysregulated cellular programmes in the inflamed epithelium of Crohn's disease patients
Single-cell analysis of Crohn's disease reveals a detailed picture of
Workshops Broad Institute
Peter V. on LinkedIn: Single-cell analysis of Crohn's disease
Single cell analysis of Crohn's disease patient-derived small intestinal organoids reveals disease activity-dependent modification of stem cell properties