Fig. 6.1 Achieving steady state with the use of: (A) a constant infusion (B) intermittent bolus dosing (C) an initial loading dose followed by intermittent doses A single bolus dose (loading dose) administered before the constant infusion or intermittent bolus doses (Fig. 6.1C) can accelerate the achievement of steady state. Here, the main factor determining the…

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PDF] Analytical modeling and correction of steady state relative permeability experiments with capillary end effects – An improved intercept method, scaling and general capillary numbers