The literature on pharmacologic treatments for postural orthostatic tachycardia syndrome (POTS) is inconsistent and unstandardized. Therefore, we aimed to evaluate choices in pharmacologic treatment options for POTS and the challenges encountered in the studies. We searched numerous databases like PubMed, Scopus, Embase, Web of Science, and Google Scholar for literature published before April 8, 2023. The search was done to retrieve potential peer-reviewed articles that explored drug therapy in POTS. Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were used to conduct the systematic review. Of the 421 potential articles assessed, 17 met the inclusion criteria. Results demonstrated that pharmacologic treatment options for POTS were effective in reducing symptoms of POTS, but most of the studies were underpowered. Several were terminated due to various reasons. Midodrine ivabradine, bisoprolol, fludrocortisone, droxidopa, desmopressin, propranolol, modafinil, methylphenidate, and melatonin have been studied with positive impact but sample sizes that were low in the range of 10-50 subjects. Therefore, we concluded the treatment options effectively improve symptoms of POTS and increase orthostatic tolerance, but more evidence is needed as most studies had a low sample size and thus are underpowered.
Women and Musculoskeletal Health: How Your Body Benefits from Exercise Therapy
Cureus, COVID-19 Induced Postural Orthostatic Tachycardia Syndrome (POTS): A Review
Cervical Vertigo and Cervicogenic Dizziness – Neck pain and dizziness – Caring Medical Florida
Cureus Targeting Weakness With a Combination of Isotonic Exercises in Dermatomyositis With Polyneuropathy: A Case Report
The International Network on Oesophageal Atresia (INoEA) consensus guidelines on the transition of patients with oesophageal atresia–tracheoesophageal fistula
Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation
Healthcare, Free Full-Text
Cervical dystonia and spasmodic torticollis treatment – Caring Medical Florida
Brain Sciences, Free Full-Text
Volume 22 Issue 4 by Western Journal of Emergency Medicine - Issuu
Frontiers Premature drug reduction after subthalamic nucleus deep brain stimulation leading to worse depression in patients with Parkinson's disease
Cureus Physical Rehabilitation Crucial in Motor Axonal Neuropathy Following Organophosphorus Poisoning: A Case Study
Autonomic Dysfunction And Postural Orthostatic Tachycardia, 49% OFF
Cervical dystonia and spasmodic torticollis treatment – Caring Medical Florida
What does it mean to be a Pain Free Athlete?